MARIA C. VILLA-MORALES

Work

Universidad Autónoma de Madrid

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Titular de Universidad

Spain

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Universidad Autónoma de Madrid, Facultad de Ciencias

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Profesor Contratado Doctor

Spain

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Publications

Improved identification of T‐ALL paediatric patients with low MRD but poor prognosis using a transcriptional signature

British Journal of Haematology

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PIM1 is a potential therapeutic target for the leukemogenic effects mediated by JAK/STAT pathway mutations in T-ALL/LBL

Npj Precision Oncology

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The JAK3Q988P mutation reveals oncogenic potential and resistance to ruxolitinib

Molecular Carcinogenesis

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The JAK3Q988P mutation reveals oncogenic potential and resistance to ruxolitinib

Molecular Carcinogenesis

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PIM1 is a potential therapeutic target for the leukemogenic effects mediated by JAK/STAT pathway mutations in T-ALL/LBL

npj Precision Oncology

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SOCS3 deregulation contributes to aberrant activation of the JAK/STAT pathway in precursor T-cell neoplasms

British Journal of Haematology

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Identification of NRF2 Activation as a Prognostic Biomarker in T-Cell Acute Lymphoblastic Leukaemia

International Journal of Molecular Sciences

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Identification of NRF2 Activation as a Prognostic Biomarker in T-Cell Acute Lymphoblastic Leukaemia

International Journal of Molecular Sciences

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Identification of fatty acid amide hydrolase as a metastasis suppressor in breast cancer

Nature Communications

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Identification of NRF2 Activation as a Prognostic Biomarker in T-Cell Acute Lymphoblastic Leukaemia

International Journal of Molecular Sciences

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Identification of fatty acid amide hydrolase as a metastasis suppressor in breast cancer

Nature Communications

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Comprehensive characterization of a novel, oncogenic and targetable SEPTIN6::ABL2 fusion in T‐ALL

British Journal of Haematology

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Comprehensive characterization of a novel, oncogenic and targetable SEPTIN6::ABL2 fusion in T-ALL

British Journal of Haematology

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SOCS3 deregulation contributes to aberrant activation of the JAK/STAT pathway in precursor T‐cell neoplasms

British Journal of Haematology

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A Dual Role for FADD in Human Precursor T-Cell Neoplasms

International Journal of Molecular Sciences

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A Dual Role for FADD in Human Precursor T-Cell Neoplasms

International Journal of Molecular Sciences

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Exploiting the passenger ACO1-deficiency arising from 9p21 deletions to kill T-cell lymphoblastic neoplasia cells

Carcinogenesis

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Downregulation of specific FBXW7 isoforms with differential effects in T-cell lymphoblastic lymphoma

Oncogene

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Exploiting the passenger ACO1-deficiency arising from 9p21 deletions to kill T-cell lymphoblastic neoplasia cells

Carcinogenesis

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Detection of novel fusion-transcripts by RNA-Seq in T-cell lymphoblastic lymphoma

Scientific Reports

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Detection of novel fusion-transcripts by RNA-Seq in T-cell lymphoblastic lymphoma

Scientific Reports

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Downregulation of specific FBXW7 isoforms with differential effects in T-cell lymphoblastic lymphoma.

Oncogene

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Downregulation of specific FBXW7 isoforms with differential effects in T-cell lymphoblastic lymphoma

Oncogene

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FADD in cancer: Mechanisms of altered expression and function, and clinical implications

Cancers

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FADD in Cancer: Mechanisms of Altered Expression and Function, and Clinical Implications

Cancers

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S194-P-FADD as a marker of aggressiveness and poor prognosis in human T-cell lymphoblastic lymphoma

Carcinogenesis

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S194-P-FADD as a marker of aggressiveness and poor prognosis in human T-cell lymphoblastic lymphoma.

Carcinogenesis

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S194-P-FADD as a marker of aggressiveness and poor prognosis in human T-cell lymphoblastic lymphoma

Carcinogenesis

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RNA-Seq reveals the existence of a CDKN1C-E2F1-TP53 axis that is altered in human T-cell lymphoblastic lymphomas

BMC Cancer

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Contribution of JAK2 mutations to T-cell lymphoblastic lymphoma development

Leukemia

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Deregulated FADD expression and phosphorylation in T-cell lymphoblastic lymphoma

Oncotarget

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Deregulated FADD expression and phosphorylation in T-cell lymphoblastic lymphoma

Oncotarget

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Contribution of JAK2 mutations to T-cell lymphoblastic lymphoma development.

Leukemia

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Role of Cannabinoid Receptor CB2 in HER2 Pro-oncogenic Signaling in Breast Cancer

Jnci-Journal of the National Cancer Institute

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Role of cannabinoid receptor CB2 in HER2 pro-oncogenic signaling in breast cancer

Journal of the National Cancer Institute

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FAS system deregulation in T-cell lymphoblastic lymphoma

Cell Death and Disease

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FAS system deregulation in T-cell lymphoblastic lymphoma

Cell Death & Disease

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FAS system deregulation in T-cell lymphoblastic lymphoma.

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Down-regulation of specific miRNAs enhances the expression of the gene Smoothened and contributes to T-cell lymphoblastic lymphoma development

Carcinogenesis

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Down-regulation of specific miRNAs enhances the expression of the gene Smoothened and contributes to T-cell lymphoblastic lymphoma development

Carcinogenesis

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Down-regulation of specific miRNAs enhances the expression of the gene Smoothened and contributes to T-cell lymphoblastic lymphoma development.

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Targeting the Fas/FasL signaling pathway in cancer therapy

Expert Opinion on Therapeutic Targets

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Targeting the Fas/FasL signaling pathway in cancer therapy

Expert Opinion on Therapeutic Targets

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EPHA7, a new target gene for 6q deletion in T-cell lymphoblastic lymphomas

Carcinogenesis

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EPHA7, a new target gene for 6q deletion in T-cell lymphoblastic lymphomas.

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EPHA7, a new target gene for 6q deletion in T-cell lymphoblastic lymphomas

Carcinogenesis

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Targeting the Fas/FasL signaling pathway in cancer therapy.

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The effectiveness of Fas apoptosis signalling pathway determined by the combined action of functional polymorphisms at Fas, FasL and Fadd

Ejc Supplements

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The stromal gene encoding the CD274 antigen as a genetic modifier controlling survival of mice with γ-radiation-induced T-cell lymphoblastic lymphomas.

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Modulation of the Fas-apoptosis-signalling pathway by functional polymorphisms at Fas, FasL and Fadd and their implication in T-cell lymphoblastic lymphoma susceptibility

Carcinogenesis

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Modulation of the Fas-apoptosis-signalling pathway by functional polymorphisms at Fas, FasL and Fadd and their implication in T-cell lymphoblastic lymphoma susceptibility.

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Modulation of the Fas-apoptosis-signalling pathway by functional polymorphisms at Fas, FasL and Fadd and their implication in T-cell lymphoblastic lymphoma susceptibility

Carcinogenesis

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Oncogenic function of smoothened in T-cell lymphoblastic lymphomas

Ejc Supplements

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The stromal gene encoding the CD274 antigen as a genetic modifier controlling survival of mice with gamma-radiation-induced T-cell lymphoblastic lymphomas

Oncogene

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The stromal gene encoding the CD274 antigen as a genetic modifier controlling survival of mice with γ-radiation-induced T-cell lymphoblastic lymphomas

Oncogene

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A role for auxiliary TGF-beta receptor endoglin as a modulator of tumor progression

Ejc Supplements

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A role for stroma-derived annexin A1 as mediator in the control of genetic susceptibility to T-cell lymphoblastic malignancies through prostaglandin E2 secretion.

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A role for stroma-derived annexin A1 as mediator in the control of genetic susceptibility to T-cell lymphoblastic malignancies through prostaglandin e 2 secretion

Cancer Research

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A Role for Stroma-Derived Annexin A1 as Mediator in the Control of Genetic Susceptibility to T-Cell Lymphoblastic Malignancies through Prostaglandin E-2 Secretion

Cancer Research

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Cd274/Pdc1I1 as a genetic modifier controlling aggressiveness of T-cell lymphoblastic lymphoma

Ejc Supplements

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Modulation of the susceptibility to T cell lymphoblastic lymphoma by Fas/FasL system: functional polymorphisms at Fas, FasL and Fadd

Ejc Supplements

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Genetically modified mouse models in cancer studies

Clinical and Translational Oncology

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Genetically modified mouse models in cancer studies.

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Genetically modified mouse models in cancer studies

Clinical & Translational Oncology

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A Role for the Fas/FasL System in Modulating Genetic Susceptibility to T-Cell Lymphoblastic Lymphomas

Cancer Research

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A role for the Fas/FasL system in modulating genetic susceptibility to T-cell lymphoblastic lymphomas.

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A role for the Fas/FasL system in modulating genetic susceptibility to T-cell lymphoblastic lymphomas

Cancer Research

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A role for endoglin as a suppressor of malignancy during mouse skin carcinogenesis

Cancer Research

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A role for endoglin as a suppressor of malignancy during mouse skin carcinogenesis

Cancer Research

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A role for the Fas/FasL system in modulating genetic susceptibility to T-cell lymphoblastic lymphomas

Ejc Supplements

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A role for endoglin as a suppressor of malignancy during mouse skin carcinogenesis.

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Functional Fas (Cd95/Apo-1) promoter polymorphisms in inbred mouse strains exhibiting different susceptibility to γ-radiation-induced thymic lymphoma

Oncogene

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Functional Fas (Cd95/Apo-1) promoter polymorphisms in inbred mouse strains exhibiting different susceptibility to gamma-radiation-induced thymic lymphoma.

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Functional Fas (Cd95/Apo-1) promoter polymorphisms in inbred mouse strains exhibiting different susceptibility to gamma-radiation-induced thymic lymphoma

Oncogene

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Lack of correlation between DNA copy number and mRNA expression levels of c-myc in gamma-radiation-induced mouse thymic lymphomas by using quantitative real-time PCR.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

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